French President Hollande has been told that the EgyptAir flight MS804 heading from Paris to Cairo may have crashed.
The plane, according to CNN quoting President Hollande, may have crashed over the Mediterranean sea within Egypt shore.
EgyptAir plane plane disappeared from radar with 66 people on board, the Egyptian airline on Thursday morning.
The Airbus A320 left the French capital’s Charles De Gaulle Airport at 11:09pm local time on Wednesday night and then went missing, three hours and 40 minutes into its journey.
The plane vanished 10 minutes into Egyptian airspace over the Mediterranean Sea, 20 minutes before it was due to land.
It was supposed touch down at 3:05am local time. There were 59 passengers and 10 crew on the flight.
The airline tweeted: “An informed source at EGYPTAIR stated that Flight no MS804,which departed Paris at 23:09 (CEST), heading to Cairo has disappeared from radar.’
They added that the plane disappeared 10 miles into Egyptian airspace at 37,000ft.
The airline said it was fading when air traffic control lost contact with the plane at 02:45 Cairo time.
Egyptian officials have already sent out search and rescue teams.