The Nigeria Centre for Disease Control (NCDC) confirmed 288 new cases on Friday, but the deaths rate raise to 171.
The agency announced the new cases via a tweet on its handle just before midnight.
A total of 5,445 confirmed COVID-19 cases have now been recorded in 34 states and the federal capital territory (FCT).
The number of recoveries increased from 1,180 to 1,320, while four fatalities were recorded, bringing the total number of deaths to 171.
Nigeria recorded its highest number of COVID-19 recoveries in one week on Friday, with 140 patients discharged.
Also, after almost one week of recording a steady drop in its figures, from 183 COVID-19 cases on May 7 to as low as 58 cases on May 14, the infection rate in Lagos saw a significant spike on Friday.